Most “silent” mutations are actually harmful

cancer genetic mutation dna illustration

Synonymous mutations have long been thought to have relatively no effect.

A new study reveals that most “silent” mutations are harmful rather than neutral.

Marshall Nirenberg, a graduate of the University of Michigan, and a small group of researchers deciphering the genetic code of life in the early 1960s discovered the basis by which information is stored in[{” attribute=””>DNA molecules is converted into proteins, the functional components of living cells.

They discovered three-letter DNA units called codons that describe each of the 20
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